| Sheffield 
              University Development 
              of computational methods for 3D similarity and structure-based design 
              techniques in lead optimisation (EPSRC CASE)  The lead optimisation 
              phase of drug discovery involves successive cycles of design and 
              synthesis in order to identify structures within a chemical series 
              that have desired properties. This project involves the development 
              of software tools based on 3D similarity methods to assist in this 
              process.  URL: NONE 
              Contact: Dr. Val Gillet, Senior Lecturer, [email protected]
 Dates: October 2002 - September 2005
 Funding: GlaxoSmithKline
 
 BFIT: Barnsley 
              Fast Track to Information Technology-phase 3  This project 
              is concerned with the employment and training of computer support 
              technicians from the Barnsley area.  URL: 
              NONEContact: Prof. Bob Usherwood, [email protected]
 Dates: September 2002-August 2003
 Funding: The National Council on Archives
 
 Analysis 
              and comparison of three-dimensional nucleic acid structures This project 
              is developing computational methods, based on graph theory, for 
              searching for patterns of bases in nucleic acid 3D structures. The 
              methods are being developed as part of an ongoing collaboration 
              with the Department of Molecular Biology and Biotechnology in the 
              University of Sheffield, and will be based on previous joint studies 
              of search tools for 3D protein structures. URL: NONEContact: Prof. Peter Willett, Professor, [email protected]
 Dates: October 1999 � September 2002
 Funding: BBSRC-Bioinformatics Programme
 
 The Archives and Records Management Workforce Study: 
              recruitment, training and leadership for the UK sector The project will help the sector to retain, 
              support and develop a workforce appropriate to its current and future 
              needs. It will seek to create a coherent framework for future professional 
              recruitment, education, training and development, and help to improve 
              responsiveness to change. It will increase the amount and quality 
              of information available to managers, educators, and selectors, 
              leading to more effective decision- making. URL: NONEContact: Prof. Bob Usherwood, [email protected]
 Dates: September 2002-August 2003
 Funding: The National Council on Archives
 
 CLARITY: 
              Cross language information retrieval and organization of text and 
              audio documents CLARITY is an 
              EU-funded research project with the aim to provide a cross language 
              information retrieval system for text and audio documents. See 
              web site at clarity.shef.ac.uk Contact: Dr. Mark Sanderson, Lecturer, [email protected]Dates: December 2000 � November 2003
 Funding: EC-Framework V Research & Technological 
              Developments
 
 Computer 
              analysis of high throughput screening data (EPSRC CASE) This project is developing computational 
              methods for the analysis of the large volumes of structural and 
              bioactivity data generated by high-throughput screening progarmmes 
              in the pharmaceutical and agrochemical industries. URL: NONEContact: Prof. Peter Willett, Professor, [email protected]
 Dates: October 1999 � September 2002
 Funding: Eli Lilly
 
 Concept-based 
              interactive query expansion support tool (CIQUEST) An investigation into a novel approach for 
              clustering documents to generate concepts displayed as hierarchies 
              for supporting interactive query expansion. A major emphasis is 
              to develop a user-based evaluation of the concept tool. URL: NONEContact: Professor Micheline Beaulieu, Head 
              of Department, [email protected]
 Dates: May 2000 � February 2003
 Funding: Re:source
 
 The 
              development of a novel descriptor targeted to high-throughput analysis 
              in lead exploration and combinatorial library design (BBSRC CASE) Nothing published yet so still confidential URL: NONEContact: Prof. Peter Willett, Professor, [email protected]
 Dates: October 2000 � September 2003
 Funding: Novartis Pharmaceuticals UK Ltd.
 
 Development 
              of a similarity searching algorithm for the virtual screening of 
              natural product databases Similarity searching 
              is an important component of modern systems for handling databases 
              of small (drug-sized) chemical molecules. This project is evaluating 
              the appropriateness of such searching methods for databases of natural 
              product molecules.  URL: NONEContact: Prof. Peter Willett, Professor, [email protected]
 Dates: October 2000 � September 2002
 Funding: Unilever Research
 
 Development 
              of reduced graphs as novel descriptors for identifying structure-activity 
              relationships (EPSRC CASE) Nothing published yet so still confidential URL: NONEContact: Dr. Val Gillet, Senior Lecturer, 
              [email protected]
 Dates: October 2000 � September 2003
 Funding: AstraZeneca
 
 Digital 
              libraries, text archives and e-text centers: a history of the formation 
              and development of electronic text collections in the humanities 
              1970 to 2001 This project aims to examine the history 
              of the formation and development of electronic text collections 
              in the humanities both in Britain and in the USA. URL: NONEContact: Dr. Claire Warwick, Lecturer, [email protected]
 Dates: October 2001 � October 2002
 Funding: The British Academy
 
 Discrete 
              mathematical approaches to chemical information retrieval This project is developing new methods for 
              similarity searching in databases of 2D chemical structures, focusing 
              on similarity measures that are based on maximum common subgraph 
              isomorphism algorithms.  URL: NONEContact: Prof. Peter Willett, Professor, [email protected]
 Dates: October 2000 � September 2003
 Funding: Parke-Davis Pharmaceutical Research Inc.
 
 Education 
              for evidence-based citizenship: improving pupil's information seeking 
              skills This project is concerned with the investigation 
              of secondary school pupil's information seeking skills. URL: NONEContact: Mr. Nigel Ford, Reader, [email protected]
 Dates: July 2001 � June 2004
 Funding: AHRB
 
 Genome analysis 
              using DNA structure This project is developing new methods for 
              substructure and similarity searching in computed 3D nucleic acid 
              structures, in collaboration with the Department of Chemistry in 
              the University of Sheffield.  URL: NONEContact: Prof. Peter Willett, Professor, [email protected]
 Dates: January 2001 � December 2003
 Funding: BBSRC-Bioinformatics Programme
 
 Libraries must also be buildings? A new library impact 
              study With the advent of ICT the idea of the public 
              library as a physical space and the role it plays in the wider community 
              is coming into question. The opening of several new library buildings 
              in the past year provides a unique opportunity to assess the impact 
              some of these new public library buildings have on their user communities. 
              In making this assessment the research will identify the variables 
              that affect the kind of impact that is made, and develop a methodology 
              for the future assessment of impact URL: NONEContact: Prof. Bob Usherwood, [email protected]
 Dates: April 2002 � July 2002
 Funding: Resource
 
 Methods 
              for focussed combinatorial library design (BBSRC CASE) Nothing published yet so still confidential URL: NONEContact: Dr. Val Gillet, Senior Lecturer, 
              [email protected]
 Dates: October 2000 � September 2003
 Funding: GlaxoWellcome Research and Development
 
 MIND: Resource 
              selection and data fusion for multimedia international digital libraries The key objective of the MIND project is 
              to address the problems faced by users in terms of their ability 
              to access and exploit the increasing number of Digital Libraries 
              available internationally through networks, such as the Internet 
              and the World Wide Web (WWW).  URL: NONEContact: Dr. Mark Sanderson, Lecturer, [email protected]
 Dates: January 2001 � July 2003
 Funding: EC-Framework V Research & Technological 
              Developments
 
 MOSART: Music 
              orchestration systems in algorithmic research and technology This is a research 
              training and mobility network project in the area of music informatics. 
              The project task addresses the following areas: (i) Analysis of 
              Current Methods for Music Orchestration Systems; (ii) Musical Sound 
              Understanding and Timbre Modelling; (iii) Control and Virtualisation 
              of Instruments; (iv) Interactive Musical Performance; (v) Symbolic 
              Recognition of Musical Patterns and Recomposition; (vi) Symbolic 
              Recognition of Musical Patterns and Recomposition; (vii) Transfer 
              and Exploitation. Sheffield is the co-ordinating site for work in 
              area (vi). URL: NONEContact: Dr. Barry Eaglestone, Senior Lecturer, 
              [email protected]
 Dates: September 2000 � August 2003
 Funding: EC-Framework V Research Networks
 
 Probabilistic 
              prediction of bioactivity using structural descriptors Nothing published yet so still confidential URL: NONEContact: Prof. Peter Willett, Professor, [email protected]
 Dates: November 2000 � November 2003
 Funding: Syngenta
 
 Relevant 
              repositories of public knowledge? Perceptions of archives, libraries 
              and museums in modern Britain Using qualitative 
              and quantiative methodologies and by focusing on Britons� perceptions 
              and use of archives, libraries and museums when seeking information, 
              and attempting to understand, contemporary issues, the project will 
              assess the value of these traditional repositories of public knowledge 
              in the �information age� URL: NONEContact: Prof. Bob Usherwood, [email protected]
 Dates: Oct 2002 � September 2004
 Funding: AHRB
 
 SPIRIT: Spatially 
              aware information retrieval on the Internet SPIRIT will investigate the applications 
              of geographical information systems (GIS) to enhance text-based 
              information retrieval (IR) systems. Sheffield�s part in the project 
              is to adapt an existing text retrieval system to search a 1 Tb Web 
              collection using acluster of c-ordinated Unix/Linux machines (probably 
              a Beowulf cluster); find means of evaluating the accuracy of the 
              searching system; and integrate GIS information into the text searching 
              system. URL: NONEContact: Dr. Mark Sanderson, Lecturer, [email protected]
 Dates: May 2002 � April 2005
 Funding: EC-Framework V Research & Technological 
              Developments
 
 UK academics� 
              perceptions of, and pedagogy for, information literacy This project will look at UK academics� conceptions 
              of information literacy, thereby identifying implications for information 
              literacy teaching. The methodology is sensitive to individual and 
              disciplinary differences and seeks to formulate models and a framework 
              for educational practice URL: http://dis.shef.ac.uk/literacy/project/Contact: Ms. Sheila Webber, Lecturer, [email protected]
 Dates: November 2002 � October 2005
 Funding: AHRB
 
 The vital 
              link: reader development and adult basic skills This joint project with the university's 
              Department of Education is concerned with the evaluation of the 
              effectiveness of reader development strategies in terms of their 
              contribution to reducing the number of people with poor basic skills URL: NONEContact: Prof. Bob Usherwood, Professor, [email protected]
 Dates: September 2001 � August 2002
 Funding: DCMS/Wolfson Public Libraries Challenge Fund
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